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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHX8
All Species:
14.55
Human Site:
S220
Identified Species:
26.67
UniProt:
Q14562
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14562
NP_004932.1
1220
139315
S220
R
E
R
N
K
V
K
S
R
Y
R
S
R
S
R
Chimpanzee
Pan troglodytes
Q7YR39
1044
119631
K148
E
E
A
S
E
K
G
K
K
K
T
G
G
S
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537627
1216
138553
S216
R
E
R
N
K
G
K
S
R
Y
R
S
R
S
R
Cat
Felis silvestris
Mouse
Mus musculus
A2A4P0
1244
142553
S244
R
E
R
T
K
G
K
S
R
Y
R
S
R
S
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418105
1076
123154
S180
R
H
R
S
R
S
R
S
R
S
R
T
R
D
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002663993
1210
138002
R214
N
E
R
D
R
R
K
R
R
S
R
W
H
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610928
1242
141917
R213
K
E
R
R
R
R
S
R
S
R
D
N
R
R
R
Honey Bee
Apis mellifera
XP_623289
1192
136394
S199
R
D
R
R
H
H
R
S
R
D
R
K
R
S
R
Nematode Worm
Caenorhab. elegans
Q09530
1200
135741
R196
R
D
R
D
R
R
D
R
D
R
D
R
D
R
G
Sea Urchin
Strong. purpuratus
O17438
455
51461
Poplar Tree
Populus trichocarpa
XP_002318357
1207
137837
G211
H
G
Y
D
R
E
D
G
G
G
E
R
E
R
R
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38953
1168
134139
D189
G
D
G
G
E
G
E
D
R
R
R
D
R
R
A
Baker's Yeast
Sacchar. cerevisiae
P24384
1145
129992
G199
G
C
F
V
Q
I
F
G
T
R
M
K
N
C
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40
N.A.
98.5
N.A.
96.8
N.A.
N.A.
N.A.
84
N.A.
91.1
N.A.
69.4
71.8
61.3
21.9
Protein Similarity:
100
59
N.A.
99.1
N.A.
97.3
N.A.
N.A.
N.A.
86.8
N.A.
94.5
N.A.
82
83.9
75.4
28.8
P-Site Identity:
100
13.3
N.A.
93.3
N.A.
86.6
N.A.
N.A.
N.A.
46.6
N.A.
46.6
N.A.
26.6
53.3
13.3
0
P-Site Similarity:
100
40
N.A.
93.3
N.A.
86.6
N.A.
N.A.
N.A.
73.3
N.A.
60
N.A.
46.6
66.6
33.3
0
Percent
Protein Identity:
59.1
N.A.
N.A.
59.3
44.2
N.A.
Protein Similarity:
75
N.A.
N.A.
75.4
62.8
N.A.
P-Site Identity:
6.6
N.A.
N.A.
20
0
N.A.
P-Site Similarity:
20
N.A.
N.A.
40
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
8
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
24
0
24
0
0
16
8
8
8
16
8
8
8
8
% D
% Glu:
8
47
0
0
16
8
8
0
0
0
8
0
8
0
0
% E
% Phe:
0
0
8
0
0
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
16
8
8
8
0
24
8
16
8
8
0
8
8
0
8
% G
% His:
8
8
0
0
8
8
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
0
0
0
24
8
31
8
8
8
0
16
0
0
8
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
8
0
0
16
0
0
0
0
0
0
0
8
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
47
0
62
16
39
24
16
24
54
31
54
16
54
31
62
% R
% Ser:
0
0
0
16
0
8
8
39
8
16
0
24
0
47
0
% S
% Thr:
0
0
0
8
0
0
0
0
8
0
8
8
0
0
0
% T
% Val:
0
0
0
8
0
8
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
0
0
24
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _